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Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients
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《医学前沿(英文)》 2017年 第11卷 第1期 页码 53-61 doi: 10.1007/s11684-017-0502-2
Low adherence to secondary prevention medications (ATM) of patients after acute coronary syndrome (ACS) is associated with poor clinical outcomes. However, literature provides limited data on assessment of ATM and risks associated with poor in Chinese patients with ACS. In the current work, ATM was assessed in consecutively recruited patients with ACS in Tongji Hospital from November 5, 2013 to December 31, 2014. A total of 2126 patients were classified under low adherence (proportion of days covered (PDC)<50%) and high adherence (PDC>50%) groups based on their performance after discharge. All patients were followed up at the 1st, 6th, and 12th month of discharge while recording ATM and major adverse cardiac events (MACE). Bivariate logistic regression was used to identify the factors associated with ATM. Cox regression was used to analyze the association between ATM and MACE within one year after discharge. Results showed that coronary artery bypass grafting (CABG) alone had significantly lower proportion of high adherence to P2Y12 antagonists (83.0% vs. 90.7%, P<0.01) than patients treated with percutaneous coronary intervention (PCI) only. Moreover, in patients undergoing PCI, high adherence to P2Y12 antagonists decreased the risk of MACE (hazard ratio=0.172, 95% confidence interval: 0.039–0.763; P=0.021). In conclusion, PCI-treated patients are more prone to remaining adherent to medications than CABG-treated patients. High adherence to P2Y12 antagonists was associated with lower risk of MACE.
关键词: acute coronary syndromes adherence to secondary prevention medications clinical outcome
Health: a dream from reality to the future
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《医学前沿(英文)》 2016年 第10卷 第2期 页码 233-235 doi: 10.1007/s11684-016-0444-0
This paper argues that health is a realistic productive force that may enhance the index of happiness. As the basis of all developments and the source of a person’s and his/her family’s happiness, health requires not only primary and secondary prevention, but also policy prevention, that is to say, grade-zero prevention. Therefore, people should pay more attention to Health in All Policies. As a new preventive strategy, the policy prevention will help improve people’s health significantly and promote the concepts of “Healthy China” and “the Chinese Dream” or “the World Dream” to realize a dream from reality to the future.
关键词: health promotion primary and secondary prevention policy prevention infectious disease non-communicable disease
《环境科学与工程前沿(英文)》 2021年 第15卷 第4期 doi: 10.1007/s11783-020-1368-0
• SMX was mainly degraded by hydrolysis, isoxazole oxidation and double-bond addition.
关键词: Sulfamethoxazole Ozonation Natural organic matters Secondary effluent Degradation mechanism
Physical and chemical processes of wintertime secondary nitrate aerosol formation
Qi YING
《环境科学与工程前沿(英文)》 2011年 第5卷 第3期 页码 348-361 doi: 10.1007/s11783-011-0343-1
关键词: secondary nitrate aerosol N2O5 heterogeneous reaction process analysis
Two-echelon Emergency Response Problem and Simulation Considering Secondary Disasters
Han-peng Zhang,Yi Liao,Hui-xia Luo
《工程管理前沿(英文)》 2014年 第1卷 第3期 页码 318-321 doi: 10.15302/J-FEM-2014042
关键词: simulation secondary disasters two-echelon vehicle routing model
Formation of secondary inorganic aerosol in a frigid urban atmosphere
《环境科学与工程前沿(英文)》 2022年 第16卷 第2期 doi: 10.1007/s11783-021-1452-0
•Harbin showed relatively high threshold RH (80%) for apparent increase of SOR.
关键词: Haze Sulfate Nitrate Heterogeneous chemistry Biomass burning Northeast China
Haiqian LI, Yonglong LU, Li LI
《环境科学与工程前沿(英文)》 2013年 第7卷 第4期 页码 589-597 doi: 10.1007/s11783-013-0495-2
关键词:
polychlorinated dibenzo-
null
《医学前沿(英文)》 2017年 第11卷 第1期 页码 137-146 doi: 10.1007/s11684-016-0486-3
This study aims to elucidate the underlying molecular mechanisms of artemisinin accumulation induced by cadmium (Cd). The effects of different Cd concentrations (0, 20, 60, and 120 μmol/L) on the biosynthesis of Artemisia annua L. were examined. Intermediate and end products were quantified by HPLC-ESI-MS/MS analysis. The expression of key biosynthesis enzymes was also determined by qRT-PCR. The results showed that the application of treatment with 60 and 120 μmol/L Cd for 3 days significantly improved the biosynthesis of artemisinic acid, arteannuin B, and artemisinin. The concentrations of artemisinic acid, arteannuin B, and artemisinin in the 120 μmol/L Cd-treated group were 2.26, 102.08, and 33.63 times higher than those in the control group, respectively. The concentrations of arteannuin B and artemisinin in 60 μmol/L Cd-treated leaves were 61.10 and 26.40 times higher than those in the control group, respectively. The relative expression levels of HMGR, FPS, ADS, CYP71AV1, DBR2, ALDH1, and DXR were up-regulated in the 120 μmol/L Cd-treated group because of increased contents of artemisinic metabolites after 3 days of treatment. Hence, appropriate doses of Cd can increase the concentrations of artemisinic metabolites at a certain time point by up-regulating the relative expression levels of key enzyme genes involved in artemisinin biosynthesis.
关键词: Cd secondary metabolites gene expressions Artemisia annua L.
Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China
null
《医学前沿(英文)》 2014年 第8卷 第2期 页码 135-144 doi: 10.1007/s11684-014-0331-5
Chronic hepatitis B is a major health problem in China. The universal vaccination program since 1992 has changed the epidemiology of hepatitis B virus infection in China from highly to moderately endemic. The most prevalent hepatitis B virus strains in China are genotypes B and C, whereas those in western provinces are genotypes D and C/D hybrid. Chronic hepatitis B poses a heavy burden to the society in China. Different treatment strategies have been explored to improve patient outcomes in a cost-effective manner. However, antiviral drugs with a low genetic barrier to resistance are still extensively used because of the generally low income and limited resources in China. Individualized antiviral therapy is closely associated with translational medicine, which utilizes information from studies on genomics, immune biomarkers, and fibrosis. The results of these studies are crucial in further improving treatment outcomes.
Simple model of sludge thickening process in secondary settlers
Yuankai ZHANG,Hongchen WANG,Lu QI,Guohua LIU,Zhijiang HE,Songzhu JIANG
《环境科学与工程前沿(英文)》 2016年 第10卷 第2期 页码 319-326 doi: 10.1007/s11783-014-0758-6
关键词: wastewater treatment plants secondary settler sludge thickening sludge settling hindered zone
On the location of the secondary instantaneous poles in two-degree-of-freedom spherical mechanisms
Soheil ZARKANDI
《机械工程前沿(英文)》 2014年 第9卷 第1期 页码 34-40 doi: 10.1007/s11465-014-0290-1
As the instant centers in planar mechanisms, the instantaneous poles (or instant poles, in brief) can be used for kinematic analysis in spherical mechanisms. One of the mandatory steps in this analysis is the determination of the location of these poles. This paper presents a theorem showing analytically that the locus of an unknown secondary instant pole in two-degree-of-freedom (2-DOF) spherical mechanisms is a great circle (GC). The exact location of the pole on its GC is obtained based on the configuration of the mechanism and velocity ratio of the two inputs. Moreover, using the results of the theorem, a geometrical technique is presented to determine the GC of the pole.
关键词: spherical mechanisms instantaneous poles great circle angular velocity
Xiliang ZHANG, Zhiying CUI, Jianhan ZHANG, Fengwu BAI, Zhifeng WANG
《能源前沿(英文)》 2019年 第13卷 第3期 页码 590-596 doi: 10.1007/s11708-018-0602-y
关键词: secondary parabolic trough solar concentrator ray tracing method linear focus concentration ratio optical performance
Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development
Long-de Wang
《工程管理前沿(英文)》 2015年 第2卷 第1期 页码 2-12 doi: 10.15302/J-FEM-2015002
关键词: chronic disease prevention and control strategy and system construction
Relationship between the number of tapping-induced secondary laticifer lines and rubber yield among
Yueyi CHEN,Xinsheng GAO,Xiaofei ZHANG,Weimin TIAN
《农业科学与工程前沿(英文)》 2016年 第3卷 第4期 页码 363-367 doi: 10.15302/J-FASE-2016122
关键词: Hevea brasiliensis rubber yield breeding early evaluation tapping secondary laticifer differentiation
A method for quantifying bias in modeled concentrations and source impacts for secondary particulate
Cesunica E. Ivey, Heather A. Holmes, Yongtao Hu, James A. Mulholland, Armistead G. Russell
《环境科学与工程前沿(英文)》 2016年 第10卷 第5期 doi: 10.1007/s11783-016-0866-6
关键词: Particulate matter Source apportionment Secondary particulate matter Chemical transport modeling Receptor modeling
标题 作者 时间 类型 操作
Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients
null
期刊论文
Mechanisms for simultaneous ozonation of sulfamethoxazole and natural organic matters in secondary effluent
期刊论文
Two-echelon Emergency Response Problem and Simulation Considering Secondary Disasters
Han-peng Zhang,Yi Liao,Hui-xia Luo
期刊论文
PCDD/Fs emission, risk characterization, and reduction in China’s secondary copper production industry
Haiqian LI, Yonglong LU, Li LI
期刊论文
Effects of different doses of cadmium on secondary metabolites and gene expression in Artemisia annua
null
期刊论文
Simple model of sludge thickening process in secondary settlers
Yuankai ZHANG,Hongchen WANG,Lu QI,Guohua LIU,Zhijiang HE,Songzhu JIANG
期刊论文
On the location of the secondary instantaneous poles in two-degree-of-freedom spherical mechanisms
Soheil ZARKANDI
期刊论文
Optical performance analysis of an innovative linear focus secondary trough solar concentrating system
Xiliang ZHANG, Zhiying CUI, Jianhan ZHANG, Fengwu BAI, Zhifeng WANG
期刊论文
Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development
Long-de Wang
期刊论文
Relationship between the number of tapping-induced secondary laticifer lines and rubber yield among
Yueyi CHEN,Xinsheng GAO,Xiaofei ZHANG,Weimin TIAN
期刊论文